منابع مشابه
Narcotic Discrimination in Pigeons: Antagonism
S. HERLING, R.J. VALENTINO, R.E. SOLOMON and J.H. WOODS, Narcotic discrimination in pigeons." Antagonism by naltrexone, European J. Pharmacol. 105 (1984) 137-142. In pigeons trained to discriminate between morphine (10 mg/kg) and saline, both morphine and ethylketazocine produced dose-related morphine-appropriate responding. The maximum effect produced by meperidine, however, was only 60% of th...
متن کاملNaloxone for narcotic exposed newborn infants: systematic review.
BACKGROUND Naloxone, a specific opiate antagonist, is available for the treatment of newborn infants with respiratory depression that may be due to transplacentally acquired opiates. AIMS To determine if this treatment has any clinically important benefits, and whether there are any harmful effects. METHODS Randomised controlled trials that compared naloxone with placebo or no drug for newb...
متن کاملRespiratory depression due to unsuspected narcotic ingestion treated with naloxone.
Two patients are presented with respiratory depression for which no cause was apparent. Both had ingested narcotics without the parents' knowledge. Narcotic ingestion should be suspected if signs of respiratory failure with constricted pupils are present, and a diagnostic test with naloxone should be performed.
متن کاملIntranasal naloxone is a viable alternative to intravenous naloxone for prehospital narcotic overdose.
OBJECTIVE To compare the prehospital time intervals from patient contact and medication administration to clinical response for intranasal (IN) versus intravenous (IV) naloxone in patients with suspected narcotic overdose. METHODS This was a retrospective review of emergency medical services (EMS) and hospital records, before and after implementation of a protocol for administration of intran...
متن کاملBlocking of enhanced sensitivity to behavioral effects of naloxone induced by narcotic agonists in rats.
The present experiment evaluated whether prior treatment with naloxone could block the sensitization to opiate antagonist induced by single dose administration of pure agonist (morphine) or mixed agonist (buprenorphine). Food deprived male Wistar rats were trained to respond for food on a multiple-trial, fixed-interval 3 min schedule. Reinforcement was contingent upon a response within a 10-s l...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1983
ISSN: 0003-2409
DOI: 10.1111/j.1365-2044.1983.tb13926.x